Supergirl is stunned to discover that a part of Krypton survived. Meanwhile, Alex is attacked while out with Ruby, and Lena considers how far she will go to keep Reign…

When Tanya, a disciple of Coville’s, escapes from what’s left of his cult, she gives Kara and James a journal that could hold the key to saving Sam. Someone learns…

When Reign starts hunting Ruby, Supergirl and Alex work together to keep her safe. Supergirl and J’onn look to Sam’s mother for advice on how to stop Reign and come…

When Winn and the team discover an alien ship has crash landed deep underwater beneath National City, Kara/Supergirl is called in to investigate. Meanwhile, Hank attempts to bond with his…

When multiple children get sick from lead poisoning, Morgan Edge points the finger at Lena and blames her creation of the lead bomb she made to save National City from…

Kara investigates a secretive new group whose leader, Thomas Coville, has a mysterious connection to Supergirl. Meanwhile, Samantha feels like she’s letting Ruby down, and J’onn confesses an old secret.

Psi, a thief with psychic powers, attacks National City. Able to immobilize people by tapping into their worst fears, Psi proves a formidable opponent for Supergirl. Meanwhile, James and Lena…

Kara deals with the loss of Mon-El by focusing all her energy on being Supergirl and the mysterious new threat against National City. Alex confesses a secret to Maggie about…