The fifth season of the American television medical drama Grey’s Anatomy, created by Shonda Rhimes, commenced airing on American Broadcasting Company in the United States on September 25, 2008 and…

Jane and her team must fight for their lives when Roman sends deadly assassins after them. Meanwhile, Patterson goes on a date, Reade contends with the O.P.R. inquisitor, Jane and…

A CIA source threatens to tear the team apart. Rich’s place in the FBI is called into question. Roman and Crawford spend a day together under strange circumstances.