After a self-driving car crash, Nathan is uploaded to Lakeview, his girlfriend’s family’s digital after-life, where he meets his customer service rep, Nora.

Sheldon and Amy try hanging out as friends when they spend Thanksgiving together at the aquarium. Also, Wolowitz reluctantly agrees to volunteer at the soup kitchen with Bernadette, Raj and…

A sexually transmitted disease breaks out and affects several members of the hospital staff. Chief Webber promptly calls a meeting. Meanwhile, the chief reluctantly tells Dr. Derek Shepherd about his…